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As a result of risks of addiction, abuse, and misuse with opioids, even at advised doses [see Warnings and Precautions (five.one)], reserve promethazine HCl and codeine phosphate oral Answer to be used in Grownup individuals for whom the advantages of cough suppression are expected to outweigh the risks, As well as in whom an suitable assessment on the etiology of your cough has actually been built.

Drug dependancy is usually a cluster of behavioral, cognitive, and physiological phenomena that acquire immediately after recurring compound use and involves: a strong want to take the drug, problems in managing its use, persisting in its use despite hazardous effects, an increased precedence supplied to drug use than to other activities and obligations, greater tolerance, and occasionally a physical withdrawal.

All information introduced Here's not meant in its place for or different to info from well being treatment practitioners. Be sure to consult your health treatment Expert about prospective interactions or other possible complications ahead of using any product or service. The Federal Foodstuff, Drug, and Cosmetic Act need this detect.

Advertising or making a gift of Promethazine Hydrochloride and Codeine Phosphate Oral Option could harm Other people, which is from the law. Tell your Health care service provider For those who have at any time abused or been depending on Alcoholic beverages, prescription medicines or Road drugs.

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The use of codeine in promethazine HCl and codeine phosphate oral Resolution could read more obscure the prognosis or scientific program of patients with acute abdominal circumstances.

If the affected person develops these indications or symptoms, elevate the dose to your past level and taper far more slowly but surely, either by escalating the interval involving decreases, decreasing the quantity of improve in dose, or equally.

Parenteral drug abuse is usually related to transmission of infectious diseases including hepatitis and HIV.

MAOI Interaction Tell sufferers never to just take promethazine HCl and codeine phosphate oral Resolution when utilizing or in just fourteen times of halting any drugs that inhibit monoamine oxidase.

Propulsive peristaltic waves in the colon are lowered, when tone could be enhanced to The purpose of spasm leading to constipation. Other opioid-induced effects could involve a discount in biliary and pancreatic secretions, spasm of sphincter of Oddi, and transient elevations in serum amylase.

Animal Knowledge Reproductive toxicity reports have not been performed with promethazine HCl and codeine phosphate oral Answer; even so, research can be obtained with individual active substances.

Promethazine Promethazine competitively antagonize H1 receptors located in almost all of the easy muscle mass such as the gastrointestinal tract, uterus, huge blood vessels and bronchial muscle.

Lower blood pressure level. A sudden fall in blood pressure can occur in some individuals all through treatment method with Promethazine Hydrochloride and Codeine Phosphate Oral Alternative which may bring about you to definitely really feel dizzy, faint, lightheaded, or weak, especially when you get up (orthostatic hypotension). Your risk of having this problem may very well be enhanced if you're taking Promethazine Hydrochloride and Codeine Phosphate Oral Solution with specific other medicines that reduce hypertension.

Promethazine HCl and codeine phosphate oral Answer is for oral use only. Abuse of promethazine HCl and codeine phosphate oral Answer poses a hazard of overdose and Demise.

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